A great deal of the teens on the skin care board are really using a great deal of benzoyl peroxide. Ought to these goods maybe state on the label or some thing that benzoyl peroxide is utilized to induce skin cancer in lab animals for skin cancer research?

http://www.ncbi.nlm.nih.gov/websites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=2507187&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus

Department of Dermatology Skin Diseases Study Center, College Hospitals of Cleveland, OH.
It is known that the free-radical-producing compound, benzoyl peroxide (BPO) enhances malignant conversion of murine skin benign papillomas into carcinomas.
If there is such a difference in between rodent and human skin, why are they using the rodents to test skin cancer medicines for humans? What, the outcomes of the drug tests are okay and helpful for humans but how we get it is various?
FDA MedWatch…

Benzoyl peroxide has been shown to be a tumor promoter and progression agent in a
number of animal studies. The medical significance of this is unknown.
Benzoyl peroxide in acetone at doses of five and ten mg administered twice per week induced
skin tumors in transgenic Tg.AC mice in a examine using twenty weeks of topical treatment.
In a 52 week dermal photocarcinogenicity examine in hairless mice, the median time to onset
of skin tumor formation was decreased and the number of tumors per mouse
increased following chronic concurrent topical administration of BenzaClin Topical Gel
with exposure to ultraviolet radiation (forty weeks of treatment adopted by 12 weeks of
observation).

http://www.fda.gov/medwatch/Security/2005/APR_PI/BenzaClin_PI.pdf

If it is utilized to turn benign papillomas (like a pimple) to malignant papillomas in lab animals at ONLY five-ten% utilized ONLY 2 occasions a week from One supply, How can the chem producer state that it doesn’t?

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Filed under: Skin Care

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